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Hans Lilja Selected Research

Tissue Kallikreins (Tissue Kallikrein)

5/2015A Highly Sensitive Porous Silicon (P-Si)-Based Human Kallikrein 2 (hK2) Immunoassay Platform toward Accurate Diagnosis of Prostate Cancer.
9/2013Prostate-specific kallikrein-related peptidases and their relation to prostate cancer biology and detection. Established relevance and emerging roles.
11/2009Prostate-specific antigen velocity for early detection of prostate cancer: result from a large, representative, population-based cohort.
2/2007Comparison of free and total forms of serum human kallikrein 2 and prostate-specific antigen for prediction of locally advanced and recurrent prostate cancer.
2/2007Long-term prediction of prostate cancer up to 25 years before diagnosis of prostate cancer using prostate kallikreins measured at age 44 to 50 years.
3/2006Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug.
3/2006High-speed biomarker identification utilizing porous silicon nanovial arrays and MALDI-TOF mass spectrometry.
4/2005Association of free-prostate specific antigen subfractions and human glandular kallikrein 2 with volume of benign and malignant prostatic tissue.
3/2005Comparison of predictive accuracy for pathologically organ confined clinical stage T1c prostate cancer using human glandular kallikrein 2 and prostate specific antigen combined with clinical stage and Gleason grade.
11/2004Screening a combinatorial peptide library to develop a human glandular kallikrein 2-activated prodrug as targeted therapy for prostate cancer.
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Hans Lilja Research Topics

Disease

174Prostatic Neoplasms (Prostate Cancer)
04/2022 - 08/2002
66Neoplasms (Cancer)
12/2021 - 01/2002
17Neoplasm Metastasis (Metastasis)
08/2020 - 05/2006
8Circulating Neoplastic Cells
12/2021 - 04/2007
5Prostatic Diseases
09/2013 - 11/2002
4Breast Neoplasms (Breast Cancer)
11/2017 - 01/2002
4Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
01/2016 - 12/2003
3Carcinogenesis
12/2015 - 12/2009
2Genetic Predisposition to Disease (Genetic Predisposition)
01/2018 - 01/2018
2Extranodal Extension
11/2013 - 02/2007
2Chronic Renal Insufficiency
02/2012 - 04/2009
2Colorectal Neoplasms (Colorectal Cancer)
12/2008 - 08/2002
2Colonic Neoplasms (Colon Cancer)
07/2003 - 01/2002
1Multiple Endocrine Neoplasia Type 2b (MEN 3)
01/2022
1Urinary Bladder Neoplasms (Bladder Cancer)
02/2014
1Kidney Neoplasms (Kidney Cancer)
09/2013
1Adenocarcinoma
05/2012
1Ovarian Neoplasms (Ovarian Cancer)
12/2008

Drug/Important Bio-Agent (IBA)

129Prostate-Specific Antigen (Semenogelase)IBA
01/2021 - 08/2002
39Kallikreins (Kallikrein)IBA
04/2022 - 02/2007
34Biomarkers (Surrogate Marker)IBA
01/2022 - 11/2003
25Peptide Hydrolases (Proteases)FDA Link
01/2021 - 07/2003
19Tissue Kallikreins (Tissue Kallikrein)IBA
05/2015 - 08/2002
17Proteins (Proteins, Gene)FDA Link
01/2016 - 06/2003
11Androgen Receptors (Androgen Receptor)IBA
01/2021 - 04/2007
10AndrogensIBA
01/2018 - 07/2003
7Messenger RNA (mRNA)IBA
12/2015 - 08/2002
5Biological ProductsIBA
04/2015 - 11/2003
5beta-microseminoproteinIBA
02/2013 - 07/2007
4RNA (Ribonucleic Acid)IBA
01/2020 - 09/2003
4Protein Isoforms (Isoforms)IBA
11/2010 - 06/2004
4Peptides (Polypeptides)IBA
12/2009 - 07/2003
3Indicators and Reagents (Reagents)IBA
12/2016 - 07/2009
3Monoclonal AntibodiesIBA
12/2014 - 02/2012
3ThapsigarginIBA
03/2006 - 07/2003
3ProdrugsIBA
03/2006 - 07/2003
2MicroRNAs (MicroRNA)IBA
01/2021 - 12/2010
2Abiraterone AcetateIBA
07/2020 - 11/2011
2AntigensIBA
01/2020 - 11/2016
2Genetic Markers (Genetic Marker)IBA
12/2018 - 09/2014
2paraform (paraformaldehyde)IBA
11/2017 - 09/2012
2AntibodiesIBA
01/2016 - 04/2015
2Exopeptidases (Exopeptidase)IBA
11/2014 - 01/2006
2Kazal Pancreatic Trypsin InhibitorIBA
02/2014 - 06/2008
2Serine Proteases (Serine Protease)IBA
11/2011 - 12/2009
2Tumor Biomarkers (Tumor Markers)IBA
06/2011 - 12/2008
2Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
12/2008 - 05/2006
2Cysteine (L-Cysteine)FDA Link
07/2007 - 05/2006
2L12ADTIBA
03/2006 - 07/2003
2Tissue Inhibitor of MetalloproteinasesIBA
08/2002 - 01/2002
2Tissue Inhibitor of Metalloproteinase-1IBA
08/2002 - 01/2002
1Pharmaceutical PreparationsIBA
12/2021
1thiamine triphosphorate (TTP)IBA
01/2021
1ORALIT (ORS)IBA
01/2019
1SolutionsIBA
02/2018
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
01/2018
1padeliporfinIBA
01/2018
1acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamideFDA Link
01/2018
1Free RadicalsIBA
01/2018
1Epithelial Cell Adhesion MoleculeIBA
11/2017
1CI 22IBA
01/2017
1insulin receptor-related receptor (IRR)IBA
01/2017
1dimemorfan (AT 17)IBA
01/2017
1N-hydroxysuccinimide S-acetylthioacetate (SATA)IBA
11/2016
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
01/2016
1TensinsIBA
12/2015
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
12/2015
1SiliconIBA
05/2015
1Immunoglobulin G (IgG)IBA
04/2015
1Blood Proteins (Serum Proteins)IBA
12/2014
1Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA
11/2014
1AminopeptidasesIBA
11/2014
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
10/2014
1Dutasteride (Avodart)FDA Link
01/2013
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
11/2012
1EpitopesIBA
05/2012
1Dihydrotachysterol (AT 10)IBA
03/2012
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2011
1Intergenic DNA (Junk DNA)IBA
05/2010
1Finasteride (Propecia)FDA LinkGeneric
03/2010
1AldehydesIBA
12/2009
1EnzymesIBA
12/2009
1Hormones (Hormone)IBA
12/2008
1Carcinoembryonic AntigenIBA
12/2008
1Progesterone Receptors (Progesterone Receptor)IBA
12/2008
1Plasminogen Activators (Plasminogen Activator)IBA
12/2008

Therapy/Procedure

18Therapeutics
12/2021 - 07/2003
18Prostatectomy (Retropubic Prostatectomy)
01/2020 - 09/2003
11Castration
07/2020 - 04/2007
4Drug Therapy (Chemotherapy)
11/2011 - 07/2003
3Radiotherapy
01/2019 - 01/2012
2Aftercare (After-Treatment)
01/2020 - 01/2018
1Precision Medicine
01/2021
1Photochemotherapy (Photodynamic Therapy)
01/2018
1Vasectomy (Vas Occlusion)
04/2017
1Reproductive Sterilization (Female Sterilization)
04/2017
1Intravenous Injections
05/2012
1Conservative Treatment
05/2011
1Transurethral Resection of Prostate (TURP)
12/2010
1Chemoprevention
09/2010